Our supplement blends are always led by science. Lindsey notes, “A 2024 study sponsored by SiS (Science in Sport) showed that supplementation with a L-Glycine, Tart Cherry powder, Tryptophan, L-Theanine and Magnesium reduced sleep onset latency, increased total sleep duration and increased sleep efficiency – leading to reduced perceptions of morning sleepiness.” Along with these ingredients, we’ve added a few more nutritional powerhouses to the Rest & Renew blend:

• Glycine: “An amino acid that works as a neurotransmitter in the brain, Glycine has been reported in several studies to improve subjective sleep quality and sleep efficacy, shorten sleep onset latency and lessen daytime sleepiness.” Unlike most sleep supplements that include magnesium biscglycinate, “Rest & Renew offers a Glycine base – providing a higher, more efficacious dose by having Glycine alone.” 
• Tryptophan: “An amino acid that is a precursor to serotonin in the body. Serotonin is a neurotransmitter that plays a role in mood, sleep and the circadian rhythm.”
• Vitamin D: “Those with low Vitamin D levels have shown poorer sleep – we utilise the D3 form, known for its higher bioactivity.”
• Magnesium Bisglycinate: Known to support sleep, we “utilise a chelated form of Magnesium for higher bioavailability, while being gentle on the gastrointestinal tract.”
• L-Theanine: “Well recognised for rest, relaxation and sleep, L-Theanine is the component in black and green tea responsible for promoting relaxation (without the caffeine).”
• Montmorency Cherry Powder: “A natural source of phytochemicals, including melatonin. Research has shown improvements in insomnia and measures of sleep.”
• Lemon Balm: “Taken from ayurvedic medicine, Lemon Balm has been used for sleep and relaxation.”
• Chamomile: “Taken from alternative medicine, Chamomile is renowned for its relaxation properties.”

While Melatonin supplements may be widely available in the US, Lindsey says that “UK law prohibits over-the-counter sales of melatonin.” That’s where Rest & Renew comes in.

“Melatonin is a hormone naturally produced in the brain that helps regulate the body’s sleep–wake cycle (circadian rhythm),” notes Lindsey, and “Its levels rise in the evening to promote sleepiness and fall in the morning to encourage wakefulness. Light and dark exposure informs its production, and plays a role in regular menstrual cycle and brain cell health.”

Rest & Renew can enhance your body’s melatonin production. Lindsey says that “Rest & Renew supports the body’s natural circadian rhythm through selective nutrients that may promote endogenous melatonin production,” leading to a better night’s sleep.

Unlike our Targeted Support range, Morning & Night isn't a targeted supplement – it's foundational nutrition designed to boost whole body health. Our clinically proven, award-winning formula delivers 28 biologist-selected nutrients in circadian-timed doses that support your body's natural rhythm – it’s the UK’s original and bestselling dual-dose longevity formula for a reason.

The Morning collagen softgels boost energy, focus, skin immunity and mood with N-Acetyl-L-Carnitine HCl, Taurine, Coenzyme Q10 and more

The Night collagen softgels improve sleep, skin and cellular renewal with Magnesium, L-Alanine, L-Arginine and more.

To get the most from our Targeted Support range, partner your chosen Targeted Support supplements with Morning & Night – Morning & Night builds your biological architecture to noticeably improve how you look and feel, every day.