When we launched Morning & Night in 2015, the longevity supplement category didn't exist in the UK. There were multivitamins. There were isolated nutrients. But there wasn't a comprehensive, science-led formula designed specifically to support the biological foundations of healthy ageing across the body's natural 24-hour cycle.
We shaped Morning & Night around what longevity science now recognises as the six core pillars of healthy ageing: nutrition, physical activity, sleep and recovery, stress management, social connection, and avoiding harmful substances. While supplementation cannot replace lifestyle choices, it can provide the nutritional foundation that makes those choices more effective – and more sustainable over the long term.
Designed for Your Circadian Rhythm
The body doesn't operate on a single timeline – it moves through distinct phases of energy expenditure and cellular repair across day and night. Research published in Science in 2021 demonstrated that circadian alignment of nutrient intake enhances mitochondrial efficiency, cellular autophagy and metabolic health – all critical markers of longevity.
Morning & Night was designed with circadian rhythm in mind. The Morning formula supports energy production, mitochondrial function and metabolic activity during active hours, while the Night formula focuses on cellular repair, muscle recovery, collagen synthesis and deep restorative sleep. This dual-phase approach ensures the body receives the right support at the right time, working with your biology rather than against it.
Addressing the Six Pillars of Longevity
We built Morning & Night around what longevity science now recognises as the six core pillars of healthy ageing: nutrition, physical activity, sleep and recovery, stress management, social connection, and avoiding harmful substances. While supplementation cannot replace lifestyle choices, it can provide the nutritional foundation that makes those choices more effective – and more sustainable over the long term.
Designed for Your Circadian Rhythm
The body doesn't operate on a single timeline – it moves through distinct phases of energy expenditure and cellular repair across day and night. Research published in Science in 2021 demonstrated that circadian alignment of nutrient intake enhances mitochondrial efficiency, cellular autophagy and metabolic health – all critical markers of longevity.
Morning & Night was designed with this in mind. The Morning formula supports energy production, mitochondrial function and metabolic activity during waking hours, while the Night formula focuses on cellular repair, muscle recovery, collagen synthesis and deep restorative sleep. This dual-phase approach ensures the body receives the right support at the right time, working with your biology rather than against it.
Supporting the Six Pillars of Longevity
1. Nutrition: Building Blocks for Cellular Health
A balanced diet rich in whole foods is fundamental to longevity, but modern lifestyles and depleted soil quality mean nutritional gaps are increasingly common. Morning & Night provides a comprehensive micronutrient foundation, including B vitamins, vitamin C, vitamin D3, zinc, selenium and omega-3 fatty acids – nutrients essential for immune function, energy metabolism and cellular protection.
2. Physical Activity: Metabolic and Musculoskeletal Support
Physical activity – particularly resistance training – is one of the most powerful interventions for longevity. It combats sarcopenia (age-related muscle loss), supports metabolic health and maintains bone density. But exercise places demands on the body that require proper nutritional support.
The Morning formula includes biotin and B vitamins to support glucose metabolism and energy production during activity. Research in Cell Metabolism (2022) has shown that maintaining stable blood sugar and efficient mitochondrial function in midlife significantly reduces the risk of metabolic decline in later decades.
The Night formula provides magnesium and vitamin D3– a synergistic combination that supports bone mineral density and muscle function during overnight recovery. A 2024 study in The Lancet Healthy Longevity confirmed that maintaining muscle mass and bone strength in midlife is one of the most critical determinants of functional independence in older age.
3. Sleep and Recovery: The Foundation of Regeneration
Sleep is the body's most powerful regenerative tool. Quality sleep – typically 7–9 hours – allows for cognitive consolidation, physical repair and cellular cleanup processes like autophagy. Yet sleep quality naturally declines with age, making targeted support increasingly important.
The Night formula contains magnesium, which can support GABA production and serotonin synthesis – neurotransmitters essential for deep, restorative sleep. A 2022 study in Sleep Medicine Reviews demonstrated that poor sleep quality accelerates biological ageing markers and increases the risk of chronic disease.
4. Stress Management: Protecting Against Oxidative Damage
Chronic stress accelerates ageing through multiple pathways: elevated cortisol, increased inflammation and oxidative cellular damage. While techniques like mindfulness, meditation and therapy address the psychological component of stress, nutritional support can help buffer its physical effects.
Omega-3s in the Morning formula have been shown to reduce inflammatory markers and support healthy stress response. A 2023 study in Psychoneuroendocrinology found that omega-3 supplementation reduced cortisol reactivity and improved emotional regulation under stress.
Additionally, vitamin C, zinc and selenium support the body's antioxidant defence systems, helping to neutralise the free radicals generated by chronic stress. These nutrients work synergistically to protect cellular structures from stress-induced damage.
5. Social Connection: Cognitive and Emotional Vitality
Strong social bonds are consistently linked to longer, healthier lives. While supplementation cannot replace human connection, brain health and cognitive function are essential for maintaining the relationships that sustain us.
Omega-3 fatty acids, included in the Morning formula, are critical for neuronal membrane integrity and cognitive performance. A landmark 2023 study published in Nature Medicine found that higher omega-3 levels in midlife were associated with better executive function and lower dementia risk decades later.
Additionally, B vitamins support homocysteine metabolism – elevated homocysteine is a known risk factor for cognitive decline and mood disorders. By supporting brain health, Morning & Night helps maintain the cognitive clarity and emotional balance that make meaningful connection possible.
6. Avoiding Harmful Substances: Supporting Detoxification and Cellular Defence
Eliminating tobacco, excessive alcohol and harmful substances is crucial for longevity. But even in the absence of major toxins, the body faces a daily burden of environmental pollutants, processed foods and oxidative stress.
Vitamin C and selenium in the Morning formula support the body's natural detoxification pathways and cellular defence mechanisms. A 2024 review in Antioxidants highlighted that these nutrients enhance glutathione production – the body's master antioxidant – and support phase 2 liver detoxification.