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Folate – The Immune-Boosting Vitamin

Folate, also known as Vitamin B9, is most often recognised for its role in prenatal health, but Folate’s benefits extend far beyond pregnancy and foetal protection. The B vitamin is known to help in maintaining cellular integrity, cognitive function, and cardiovascular health as we age – in its bioavailable form, Folate plays a vital role in the prevention of age-related conditions, from cognitive decline to heart disease. While Folic Acid, the synthetic form of Folate, can provide some benefits, Folate is more easily absorbed by the body – and in our effort to select the most bioavailable, efficacious nutrients, we’ve changed the Folic Acid to Folate in our upgraded Morning & Night formulation for maximum impact.

What is Folate?

Folate is a water-soluble B-vitamin that occurs naturally in foods such as leafy greens, legumes, and citrus fruits. It is essential to various bodily functions, including DNA synthesis, cell division, and neurotransmitter production. Folic Acid, the synthetic form of Folate, is commonly used in supplements and fortified foods, but the body absorbs Folate in its natural form more effectively.

Recent research highlights the importance of Folate’s bioavailability – a 2020 study published in Nutrients concluded that natural Folate sources are more efficiently processed than synthetic Folic Acid, making them more effective in preventing deficiencies and promoting health, particularly in older adults whose ability to absorb nutrients declines with age.

The Top 5 Benefits of Folate

  1. Cellular Health: Folate supports DNA repair and cell regeneration, which is essential to maintaining tissue health and mitigating age-related cellular damage.

  2. Cognitive Function: Folate contributes to the production of neurotransmitters, which support brain function and help delay cognitive decline.

  3. Cardiovascular Health: By regulating homocysteine levels, Folate helps reduce the risk of cardiovascular diseases, which become more prevalent with age.

  4. Immune Support: Folate aids in the production of red and white blood cells, supporting immune function and helping the body resist age-related immune decline.

  5. Mood Regulation: Adequate Folate levels have been linked to improved mood stability and a reduced risk of depression, a common concern in older adults.

How Folate Reduces the Signs of Ageing

Folate’s role in healthy ageing is multifaceted, influencing everything from cognitive function to immune health. Here’s how Folate contributes to maintaining vitality as we age:

Cellular Health and Regeneration: As we age, the body’s ability to regenerate cells and repair DNA diminishes. Folate is essential to DNA synthesis and cellular repair, processes that are critical to maintaining healthy tissue and preventing age-related damage. A study published in The Journal of Clinical Investigation in 2021 highlighted Folate’s role in DNA repair, noting that adequate Folate levels could reduce the accumulation of genetic damage associated with ageing.

Cognitive Function: Cognitive decline is one of the most common concerns associated with ageing. Folate plays a crucial role in brain function by facilitating the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine. These neurotransmitters are vital for mood regulation and cognitive clarity. Research published in The American Journal of Clinical Nutrition found that adequate Folate levels can delay the onset of cognitive decline and reduce the risk of dementia, particularly by lowering homocysteine levels, an amino acid associated with increased dementia risk.

Cardiovascular Health: Folate is integral to cardiovascular health, primarily by regulating homocysteine levels. Elevated homocysteine is a well-established risk factor for cardiovascular diseases, including heart disease and stroke, both of which become more common with age. A 2019 study in The Lancet demonstrated that Folate supplementation can reduce homocysteine levels, thereby lowering the risk of cardiovascular diseases. As heart health is a critical concern for older adults, Folate plays an important role in maintaining cardiovascular function.

Immune Support: The immune system weakens with age, making older adults more vulnerable to infections and diseases. Folate is essential to the production of red and white blood cells, both of which are integral to immune function. A 2018 study in The Journal of Immunology confirmed that Folate supports immune cell production, which helps the body resist age-related immune decline. By maintaining healthy immune function, Folate plays a key role in protecting against illness and supporting overall health in later years.

Mood Regulation: Folate has been shown to have a significant impact on mood, with deficiency linked to increased risk of depression and anxiety. Folate’s role in neurotransmitter production means that it can directly influence emotional well-being. A 2020 study in Psychiatry Research found that Folate supplementation improved mood and reduced symptoms of depression in older adults, making it an important nutrient for mental health as we age.

How to Boost Folate’s Benefits

As we age, the body's ability to absorb Folate and other nutrients diminishes, making supplementation an effective strategy for preventing deficiencies. Our Morning & Night supplement combines Folate with other carefully calibrated Vitamins, Minerals, Amino Acids, Adaptogens and Omega 3s for advanced whole body support.

While supplementation is the gold standard in preventing age-related Folate deficiency, it is also important to incorporate Folate-rich foods into the diet. Leafy greens, beans, lentils, and citrus fruits are all excellent natural sources of Folate. However, dietary intake alone may not be sufficient for older adults, particularly those with digestive issues or poor absorption, making supplementation an important addition to ensure optimal Folate levels.

Folate and Morning & Night

From supporting cellular health and cognitive function to promoting cardiovascular and immune health, Folate plays a vital role in maintaining cellular integrity, cognitive function, cardiovascular health and more. By incorporating Folate into your daily routine with our clinically tested, award-winning Morning & Night supplement, you’ll be supporting whole body health with 28 of the world’s most powerful ingredients.

Quality assured and always third party certified, we source the best possible ingredients nature has to offer for both our supplements and skincare; harnessing their power with cutting-edge science and the latest nutraceutical technology. Everything we design takes it's lead from the body - which is why you'll never find unnecessary fillers or nasties in our products. Discover Our Ingredients

Active Ingredients by Product

Morning & Night Female Supplement
Amino Acids

Amino acids are molecules used by all living things to make proteins. They are key in various bodily functions, from protein synthesis to tissue repair to nutrient absorption.​

Cysteine HCI - A Healing Non-Essential Amino Acid

A non-essential amino acid that aids the healing process, Cysteine has been used in medicine for more than 30 years. The nutrient replenishes intracellular levels of the natural antioxidant glutathione, which is depleted by age and illness, restoring cells’ ability to fight damage from reactive oxygen species.​ Read more on Cysteine HCI here.

L-Glutamine - An Abundant Nonessential Amino Acid

Glutamine is the most abundant amino acid in the body - and is involved in more metabolic processes than any other amino acid. Glutamine supplementation has been shown to enhance immune system function and result in a lower level of infection. In conjunction with Cysteine, Glutamine supplementation has been shown to enhance glutathione stores. Read more on L-Glutamine here.

N-Acetyl-L-Carnitine HCL - An Anti-Ageing Amino Acid

N-Acetyl-L-Carnitine HCL is a form of carnitine that plays a role in energy metabolism, protecting against and repairing existing age-induced mitochondrial DNA damage, boosting mitochondrial function and improving energy turnover. Read more on N-Acetyl-L-Carnitine HCL here.

Arginine - A Multi-Tasking Amino Acid

Arginine is an amino acid, which plays an important role in the synthesis of proteins and cell division. Many studies have linked arginine to enhanced immunity and the improved release of the human growth hormone (HGH), which repairs and regenerates the body’s tissue during sleep. Read more on Arginine here.

L-Citrulline - A Nonessential Animo Acid

Citrulline is an energy-boosting amino acid that improves endurance, cognitive function and blood pressure. It improves the ammonia recycling process and nitric oxide production, which helps blood vessels relax and improves blood flow, all of which improves performance, energy and endurance. Read more on L-Citrulline here.

Taurine (synthetic) - The ‘Wonder Molecule’

An amino acid found most commonly in meat, fish and dairy products, Taurine supports the immune system, the nervous system and healthy muscle function –improving exercise performance, reducing fatigue and increasing fat burning. Taurine also supports insulin health and is a potent brain nutrient. Read more on Taurine here.

Lysine - An Essential Collagen-Producing Amino Acid

Essential in the production of collagen, which supports the growth, repair and maintenance of healthy skin, muscles and connective tissue. Lysine sustains youthful levels of collagen in the skin, and is required to produce elastin. Read more on Lysine here.

Glycine - A Powerhouse Antioxidant

One of three essential amino acids that make up the body’s powerhouse antioxidant, Glutathione – Glycine has been shown to protect DNA and reduce inflammation in the body. Read more on Glycine here.

Morning & Night Female Supplement
Vitamins

Vitamins are essential micronutrients. They each work to keep the body function properly – from protecting against infections to helping your body get energy from food and helping your blood clot properly.

Vitamin A - The All-Rounder

Vitamin A is known to contribute to healthy skin, improved cognitive function, healthy vision and a strengthened immune system. The multifunctional vitamin also acts as an antioxidant, helping to reduce cellular, molecular and tissue damage caused by free radicals. Read more on Vitamin A here.

Vitamin B1 (Thiamine) - The Energy Yielding Nutrient

Vitamin B1, otherwise known as Thiamine, is an essential vitamin involved in maintaining an efficient, energy-yielding metabolism, a resilient nervous system, healthy cardiovascular system and balanced psychological function. Read more on Vitamin B1 here.

Vitamin B5 (Pantothenic Acid) - The Brainpower Nutrient

Vitamin B5, otherwise known as Pantothenic Acid, is one of the essential nutrients needed to reduce tiredness and fatigue and improve mental performance. It contributes to the structure and function of brain cells and has an essential role in the creation of the neurotransmitters. Read more on Vitamin B5 here.

Vitamin B6 - The Hormone Support Vitamin

Vitamin B6 is an essential B vitamin known to support the healthy regulation of hormonal activity, support a strong immune system and keep tiredness and fatigue at bay. Vitamin B6 plays a role in protein metabolism and helps support a healthy function of the nervous system.​ Read more on Vitamin B6 here.

Biotin - The Skin and Hair Saviour

Biotin is a B vitamin and healthy skin, hair, and nails powerhouse. Biotin is also essential to the conversion of food into energy – reducing tiredness and fatigue, supporting balanced psychological function and healthy mucous membranes. Read more on Biotin here.

Folate (Vitamin B9) - The Body Support Vitamin

Folate is essential to the production of red and white blood cells, and to the conversion of carbohydrates into energy. Adequate vitamin B9 intake is extremely important during periods of rapid growth such as pregnancy, infancy, and adolescence. It is also vital for psychological function and a healthy immune system.​
Read more on Folate here.

Vitamin C - The Essential Nutrient

Vitamin C is an essential nutrient and an excellent antioxidant in the body. It is vital to the production and maintenance of collagen, stimulation of adrenal function and stress management. Vitamin C has been shown to stimulate the immune system by boosting the activity of white blood cells.​ Read more on Vitamin C here.

Vitamin D3 - The Fat-Soluble Vitamin

Vitamin D3 is a fat-soluble vitamin essential to normal growth and development. Its role in the absorption of calcium is key to a healthy neuromuscular system, normal blood clotting, and heart function. Read more on Vitamin D3 here.

Vitamin E - The Antioxidant Vitamin

Vitamin E is primarily known as a powerful antioxidant with immune-boosting benefits, but it also protects against cognitive decline and memory loss by protecting cells from oxidative stress.​ Read more on Vitamin E here.

Coenzyme Q10 - A Powerful Antioxidant

A powerful, fat-soluble antioxidant and anti-inflammatory produced within the body, Coenzyme Q10 is key in sustaining health and energy, but levels of the nutrient decline with age. Studies have confirmed that, due to its fat-soluble nature, the bioavailability of Coenzyme Q10 is greatly increased by its suspension in oil.​ Read more on Coenzyme Q10 here.

Lutein - An Essential for Ocular Support

A natural carotenoid closely related to Vitamin A, Lutein is an antioxidant known to support ocular health. Research shows Lutein can play a key role in protecting the retina and lens from free radicals, supporting overall eye health and vision. Read more on Lutein here.

Morning & Night Female Supplement
Minerals

Minerals are elements that come from soil and water. They are necessary for 3 key reasons: building strong bones and teeth, controlling body fluids inside and outside cells, and turning the food you eat into energy.

Selenium - The Hormonal Balance Supporter

Selenium plays a critical role in reproduction, thyroid hormone metabolism, DNA synthesis and protection from infection. The mineral also plays a vital role in boosting antioxidant activity in the body and providing protection against free radical damage.​​ Read more on Selenium here.

Zinc - The Immune System Supporter

Zinc improves immune resilience by regulating the function of white blood cells and helping to curtail the progression of viral cold and flu symptoms. Zinc is also an important nutrient for healthy growth and development, muscle repair, DNA synthesis, fertility, reproduction and sexual function.​ Read more on Zinc here.

Magnesium - The Anti-Stress Mineral

Magnesium, in the highly bioavailable form of Magnesium Malate, is a natural tranquiliser known to relax skeletal muscles and smooth muscles of blood vessels and the gastrointestinal tract. Thanks to this function, Magnesium may also be helpful for nervousness, anxiety, low energy and muscle cramps. Read more on Magnesium Malate here.

Iodine - The Thyroid-Supporting Nutrient

Iodine’s most important role is to ensure healthy thyroid function as it helps to regulate the production of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). It also supports cognitive function, a strong nervous system and a healthy, energy yielding metabolism. Read more on Iodine (from potassium iodide) here.

Morning & Night Female Supplement
Botanical Extracts

Botanical extracts are concentrated substances derived from plants, containing beneficial compounds that support various aspects of health.​

Ashwagandha - The Mental Performance-Supporting Herb

A popular Ayurvedic herb and adaptogen, Ashwagandha contributes to increased mental performance and focus. An ally during menopause, it helps address menopause-related depression and mood swings. When taken regularly, Ashwagandha can also help reduce anxiety, by boosting the production of GABA – an important natural tranquiliser in the brain. Read more on Ashwagandha here.

Sage - The Nutrient-Rich Herb

A common herb, Sage is known to improve brain function, support digestive health and provide metabolic support. During menopause, Sage is known to help alleviate associated menopausal symptoms. Read more on Sage here.

Turmeric (root) Extract - The Anti-Inflammatory Spice

A spice used in India for thousands of years in cooking and herbal medicine, Turmeric has powerful anti-inflammatory, antioxidant and antibacterial effects. It also supports the liver and detoxification pathways. Read more on Turmeric Extract here.

Morning & Night Female Supplement
Omega 3’s

Omega-3 fatty acids are essential fats that play a crucial role in brain function, heart health and reducing inflammation.​

Flaxseed Oil - A Rich Source of Essential Fatty Acids

Flaxseed oil is rich in omega-3 fatty acids in the form of alpha-linolenic acid (ALA). Omega-3 fatty acids have been shown to reduce inflammation in all systems, increase the radiance and elasticity of the skin and boost the immune system. Read more on Flaxseed Oil here.